
What are SomaSignal Tests?
Clinically meaningful
metrics
- 18 quantitative clinical metrics
Relevant to cardiovascular disease, NASH, diabetes, and more
- Reporting current health state and understanding risk
DERIVED FROM JUST
55 µl BLOOD
Simple and simultaneous sampling for all tests
Derived from models based on proteomic signatures
Validated against standard clinical measurement
for simple, straightforward
clinical trial monitoring
Simple blood test enables frequent sampling
Does not require specialized physicians/pathologists
Simple blood draw is ideal for longitudinal studies
See the technology in action
Proteomics reveals the hidden impact of interventions in diabetes | Webinar
In this Nature Research hosted webinar, speakers will discuss how proteomic models can be implemented...
THE LIQUID LIVER BIOPSY: CHARACTERIZING NASH AND NAFLD WITH SERUM PROTEIN BIOMARKERS | WEBINAR
It was recently demonstrated that the SomaScan Assay, a multiplex proteomics platform, can noninvasively and...
Liquid health check – Plasma protein patterns as comprehensive indicators of health | Webinar
In this webinar, speakers will discuss key findings and motivations for the study “Plasma protein...
How were they developed?
The SomaSignal Tests are developed by analyzing thousands of proteins in thousands of patients using the SomaScan Assay. Protein signatures revealed by the SomaScan Assay are compared against standard clinical measurements in order to identify patterns of protein changes that correlate with current health status and future trajectory using machine learning. Each pattern becomes the basis for a specific SomaSignal Test. Because each SomaSignal test is generated using data from the same 7,000 proteins, results for all of the SomaSignal Tests can be derived from a single 55µl blood sample.

Relevant Publications
Comprehensive Liquid
Health Check
Protein signatures from 17,000 samples were compared with traditional health indicators to generate 13 predictive models.
CVD risk scores
Adverse event prediction
Any or all of the tests can be obtained for a single price alone or in conjunction with the full menu of 7,000 analytes