The ability to measure 7,000 proteins at once starts with
By using uniquely modified DNA with hydrophobic functional groups, our SOMAmer® reagents achieve a greater degree of shape matching, enabling discernment between nearly identical proteins.
SOMAmer reagents are selected for slow off-rates when correctly bound to their intended target to ensure that correct proteins remain preferentially bound during rigorous washing.
Polyanionic competitors are used to universally prevent rebinding of transient, non-specific interactions. There is no such universal competitor for antibodies.
What evidence do we have that SOMAmer reagents are specific?
What are the advantages of shape-specific proteomics?
How does exquisite specificity enable 7,000 protein measurements?
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